The investigators propose to explore: 1. the acceptance by patients of once versus twice
daily dosing with asenapine, 2. the acceptance by staff of once versus twice daily dosing
with asenapine, and 3. the changes in psychopathology associated with these two dosing
strategies, in 30 patients with schizophrenia or schizoaffective disorder.
The investigators hypothesize that patient and staff acceptance will be better with once
daily dosing and that improvements in psychopathology will be similar across once daily and
twice daily dosing