COVID-19 infection has been widely spread since December 2019 and causing many comorbidities
and fatalities. The most common clinical presentation of COVID-19 patients admitted to ICUs
is respiratory failure , hypoxia and acute lung injury.
While new therapies and vaccines are urgently being investigated, they may take an inordinate
time to get to right people. Omega-3-oil has been shown to have less proinflammatory
mediators that may have immunomodulating, anti-inflammatory and antiviral effect. Two main
fatty acids in omega-3-oil including eicosapentaenoic acid and docosahexaenoic acid have
shown benefit in patients with ARDS as well.
So, the investigators proposed a randomized controlled study to evaluate the effectiveness of
omega-3-oil supplementation 2 gm PO/NGT/OGT twice daily for 28 days or till discharge or till
death in COVID-19 critically ill patients admitted to ICU who require oxygen support.