Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung Cancer
Status:
Terminated
Trial end date:
2020-03-17
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well olaparib, cediranib maleate, and standard chemotherapy
work in treating patients with small cell lung cancer. Drugs used in chemotherapy, such as
carboplatin, cisplatin, and etoposide, work in different ways to stop the growth of tumor
cells, either by killing the cells, by stopping them from dividing, or by stopping them from
spreading. Olaparib and cediranib maleate may stop the growth of tumor cells by blocking some
of the enzymes needed for cell growth. Olaparib, cediranib maleate, and standard chemotherapy
may work better in treating patients with small cell lung cancer.