Overview

Olaparib Before Surgery in Treating Participants With Localized Prostate Cancer

Status:
Terminated
Trial end date:
2019-07-03
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well olaparib works in treating participants with prostate cancer that has not spread to other parts of the body (localized). Olaparib may stop the growth of tumor cells by interfering with the activity of a substance called PARP, which is inside cells. Giving olaparib before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed.
Phase:
Phase 2
Details
Lead Sponsor:
University of Washington
Collaborators:
AstraZeneca
National Cancer Institute (NCI)
Treatments:
Olaparib
Poly(ADP-ribose) Polymerase Inhibitors