Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study)

• Status: Completed
• Trial end date: 2019-03-31
• Target enrollment: 0
• Participant gender: All

Summary

Determine the efficacy and tolerability of olanzapine for treatment of acute depression in patients with bipolar II or bipolar disorder NOS compared with lithium.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tadashi Hasegawa
• Treatments: Lithium Carbonate; Olanzapine

Criteria

Inclusion Criteria:

• major depressive episode in type2 bipolar disorder or bipolar disorder NOS.(MADRS more than 20 point)

• 18years to 65years

• subjects who sign the informed consent document

Exclusion Criteria:

• don't have Diabetes and abnormal metabolism of sugar

• not noticed as bipolar disorder

• have an organic brain disease

• pregnant or breastfeeding women

• don't have heart disease

• have actively suicidal thought(Suicidal ideation score of MADRS is 6)

• who are judged by the investigator to should be excluded from the study