To determine whether medical reduction of intraocular pressure prevents or delays the onset
of glaucomatous visual field loss and/or optic disc damage in ocular hypertensive
participants judged to be at moderate risk for developing open-angle glaucoma.
To produce natural history data to assist in identifying patients at most risk for developing
open-angle glaucoma and those most likely to benefit from early medical treatment.
To quantify risk factors for developing open-angle glaucoma among ocular hypertensive
individuals.