Octreotide in the Prevention of Postoperative Complications After Pancreaticoduodenectomy
Status:
Completed
Trial end date:
2017-04-01
Target enrollment:
Participant gender:
Summary
pancreaticoduodenectomy (PD) is the standard operation for treatment of patients with benign
and malignant pancreatic and periampullary diseases. Despite improved surgical technique and
postoperative care, the mortality rate after PD is high reaching up to 30%, due to high
incidence of postoperative complications . Pancreatic fistula (PF) is the one of the most
frequent complications of PD and the major contributor to postoperative morbidity The aim of
this study to evaluate the effect of the perioperative octreotide use after PD for prevention
of the postoperative pancreatic fistula. The secondary outcomes are overall postoperative
complications, mortality and the cost benefit relationship of the use of the perioperative
octreotide.