Overview

Octreotide in Severe Polycystic Liver Disease

Status:
Completed
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the effect of Octreotide LARĀ® on the liver volumes of patients with severe polycystic liver disease who are not candidates or decline surgical treatments such as liver cyst fenestration, liver resection or liver transplantation. A total of 42 patients will be recruited -14 who will receive placebo and 28 the study drug. Preliminary evidence indicates that this drug is safe and non-toxic in other disease states. Treatment with this drug holds promise not only for individuals with liver involvement, but also for many more patients with polycystic kidney disease.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
National Center for Research Resources (NCRR)
Novartis
Treatments:
Octreotide