Octreotide Improves Human Lymphatic Fluid Transport a Translational Trial
Status:
Completed
Trial end date:
2021-03-26
Target enrollment:
Participant gender:
Summary
This study aims to investigate whether octreotide, a medication used off-label to treat
chylothorax, has a direct effect on human lymphatic drainage. To study the effects of
octreotide, the researchers conducted a pre-clinical experiment using human lymphatic vessels
mounted in a myograph chamber and a clinical experiment in which a double-blinded,
randomized, cross-over trial wass conducted in 16 healthy adults. The results of the study
will be used to determine the role of octreotide in the treatment of chylothorax and other
lymphatic disorders.