Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
- To determine whether the success rate with drug treatment (atropine) of amblyopia due to
strabismus or anisometropia in patients less than 7 years old is equivalent to the
success rate with occlusion (patching) therapy
- To develop more precise estimates of the success rates of amblyopia treatment
- To identify factors that may be associated with successful treatment of amblyopia
- To collect data on the course of treated amblyopia to provide more precise estimates of
treatment effects than are now available
Extended Follow up of Study Patients
- Primary: To determine the long-term visual acuity outcome at age 10 years and at age 15
years in patients diagnosed with amblyopia before age 7 years.
- Secondary: To determine whether the long-term visual acuity outcome at age 10 years and
at age 15 years differs between patients who received patching followed by best clinical
care and patients who received atropine followed by best clinical care