Obesity in Children and Adolescents: Associated Risks and Early Intervention

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators hypothesize that Metformin decreases weight, normalizes lipid profile and increases insulin sensitivity; the study team hope to get better effect of weight decrease and metabolic processes repair in the intensive treatment group with intervention of physical activity, diet correction and Metformin use.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lithuanian University of Health Sciences
• Treatments: Metformin

Criteria

Inclusion Criteria:

• Age 10-17 yrs;

• Weight > 85th percentile for age and gender (by IOTF);

• Living in Kaunas and its region;

• No obvious chronic diseases;

• Not on steroid or other long-term treatment;

• Informed consent of the patient and parents (official caregivers);

Exclusion Criteria:

• Age less than 10 or above 17 yrs;

• Diagnosis of type 1 diabetes;

• Chronic illness that may affect physical activity and metabolic profile;

• Insulin treatment;

• Steroid treatment;

• Planning to move from Kaunas or its region in the period of 1 year;

• Protocol refused by the patient or his parents;