ON-Q Pump Infusion of Ketorolac and Ropivacaine at the Wound Site for Postoperative Pain Management
Status:
Completed
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
After surgery it is normal to experience some pain at the site of operation. In order to
reduce the pain, medication such as Morphine is injected into a vein using a Patient
Controlled Analgesia (PCA) pump that is kept at bed side, and is activated by the patient
when needed. However, Morphine is an opioid drug, which can cause side effects such as
sedation, nausea, vomiting, and reduced breathing on prolonged use. In addition to the opioid
drugs, local anesthetics, and other drugs called Non steroidal anti inflammatory drugs
(NSAIDs) have been injected locally to provide prolonged pain relief without the side effects
of morphine. Recently a portable device called ON-Q pump has been developed to continuously
infuse the local anesthetic through 2 small catheters inserted at the wound site. The ON-Q
Pump is a small tennis ball sized unit made of a soft synthetic material that slowly infuses
the drug through the catheters by elastic force. This pump is very safe and is attached to a
bedside pole or the patient's hospital gown. This pump has already been approved by the FDA
for clinical use, and has been reported to provide effective pain management after some
surgical procedures.
The primary aim of the present study is to evaluate the relative efficacy of the drugs
Ketorolac and Ropivacaine infused through the ON-Q pump in reducing the pain following
gynecologic surgery. Ketorolac and Ropivacaine are approved drugs that are frequently used
for post operative pain relief. Our hypothesis is that these two drugs in combination will
provide better analgesia than Ketorolac alone.