Nutritional and Contractile Regulation of Muscle Growth
Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
Muscle wasting, which involves the loss of muscle tissue, is common in many conditions, such
as cancer, AIDS, trauma, kidney failure, bone fracture, and sepsis. It is also prevalent
among the elderly and in people who experience periods of physical inactivity and
weightlessness. Muscle wasting can lead to overall weakness, immobility, physical dependence,
and a greater risk of death when exposed to infection, surgery, or trauma. There is a need to
develop scientifically based treatments that prevent muscle wasting. As one step towards such
a goal, this study will examine the physiological and cellular mechanisms that regulate
skeletal muscle growth.
Phase:
Phase 1
Details
Lead Sponsor:
The University of Texas Medical Branch, Galveston
Collaborator:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)