Novel Approaches in Preventing and Limiting Events III Trial (NAPLES III): Bivalirudin in High-risk Bleeding Patients
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Bleeding occurring during percutaneous coronary interventions (PCI has now emerged as one of
the most common complication of PCI and adversely affect in-hospital, short- and long-term
outcome.As bivalirudin proved its effectiveness in decreasing haemorrhagic events during PCI,
its administration may be advocated in subjects deemed at high risk of bleeding.Objective of
the present trial is to compare the safety and effectiveness of procedural use of bivalirudin
in comparison to unfractionated heparin (UFH) in patients undergoing PCI deemed at high risk
of procedural bleeding.