Normal Saline Versus Heparinized Solution Flush for Maintaining Patency of Peripheral Venous Catheters in Children

• Status: Suspended
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to verify if the periodic flush with normal saline 0.9% NaCl causes a longer or equal duration of patency of peripheral venous catheters, compared with heparin solution 50 U / ml flush, in children from 2 years to 14 years. Only 22 and 24 gauge catheters Will be included in the study.The study will assess in particular:

• the difference of permanence in situ of the device

• the difference in incidence of complications (in detail: obstruction, phlebitis, thrombocytopenia, systemic anticoagulation)

• the difference in costs between use of saline normal saline 0.9% NaCl solution and heparinized 50 U / ml.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Florence
• Treatments: Calcium heparin; Heparin; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Age between 2 years and 14 years old

• Medical prescription of intravenous antibiotic therapy for at least 2 doses on the day

• Presence of informed consent to participate to the study provided by the parents

• No known hypersensitivity to heparin

• No known hypersensitivity to the patch fixing materials (polyurethane and / or glue)

• Absence of diseases buoyancy coagulation (haemophilias and / or thrombophilias)

• No antecedents trombopenie dued to the use of any type of heparin or a pentosan polysulfate

• No existing treatment based on corticosteroids and / or anti-inflammatory

Exclusion Criteria:

• age outside the range 2 - 14 years

• children for which there is no prescription of intravenous antibiotic therapy for at least 2 times a day

• children for which the parents have not consented to the study

• children with known hypersensitivity to heparin

• children with known hypersensitivity to the patch fixing materials (polyurethane and / or adhesive)

• children with disease-causing buoyancy coagulation (Hemophilia and / or thrombophilia)

• children with antecedents of trombopenie occurring by the use of any type of heparin or of a pentosan polyphosphate

• children in treatment with corticosteroids and / or anti-inflammatory