Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
- For the prevention of spontaneous bacterial peritonitis (SBP) in patients with liver
cirrhosis, norfloxacin 400mg per day is a standard regimen.
- Ciprofloxacin 750 mg per week is also known to be effective for prevention of SBP. In
addition, ciprofloxacin once weekly administration is more convenient and less costly.
- Therefore ciprofloxacin once weekly could be more useful if the the efficacy is
comparable to norfloxacin once daily.
- This study aims to prove ciprofloxacin once weekly administration is as effective as
norfloxacin once daily administration for the prevention of SBP in cirrhotic patients
with ascites.
Phase:
Phase 4
Details
Lead Sponsor:
Korea University
Collaborators:
Hanyang University Kyungpook National University Kyungpook National University Hospital Pusan National University Soon Chun Hyang University Sungkyunkwan University Yonsei University