Overview

Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock

Status:
Completed
Trial end date:
2005-12-01
Target enrollment:
Participant gender:
Summary
Catecholamines infusion is a major component of septic shock management. International guidelines recommend that norepinephrine should be preferred to epinephrine, though phase III trials are lacking. The present study aimed at comparing the efficacy and safety of norepinephrine plus dobutamine to that of epinephrine in adults with septic shock.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
University of Versailles
Collaborator:
Assistance Publique - Hôpitaux de Paris
Treatments:
Dobutamine
Epinephrine
Epinephryl borate
Norepinephrine
Racepinephrine