Norepinephrine Infusion During Cardiopulmonary Bypass
Status:
Recruiting
Trial end date:
2021-05-01
Target enrollment:
Participant gender:
Summary
The primary objective is to test the efficacy and safety of the accuracy of continuous
intravenous infusion of norepinephrine during cardiopulmonary bypass (CPB) on the prevention
of hyperlactatemia after cardiac surgery.
"Efficacy" would be tested with measurement of the postoperative changes in lactic acid level
over time from the baseline value before induction of general anesthesia.
"safety" would be tested with observing the post-cardiotomy need for inotropic and
vasopressor support, the incidence of postoperative acute kidney injury (AKI), changes in
cardiac troponin level (CnTnI), and signs of ischemic splanchnic injury.