Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
Hypertensive disorders of pregnancy are a major cause of maternal mortality and morbidity,
especially in developing countries. Postpartum hypertension can be related to persistence of
gestational hypertension, preeclampsia, or preexisting chronic hypertension, or it could
develop de novo secondary to other causes. The available data in the medical literature have
primarily focused on antenatal and peripartum management. There are few data regarding the
evaluation in women who are diagnosis with postpartum hypertension. Some medications that
cause vasoconstriction are often used for pain relief, in women having perineal lacerations,
episiotomy, or cesarean delivery. Such women usually require large doses of nonsteroidal
antiinflammatory drugs that are associated with vasoconstriction and sodium and water
retention, this drugs can result in severe hypertension.
The purpose of this study is to evaluate maternal postpartum hypertension in women with
severe preeclampsia treated with nonsteroidal antiinflammatory drugs or acetaminophen.