Noninvasive Markers of Functional Nausea in Children

• Status: Enrolling by invitation
• Trial end date: 2023-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The researchers propose to study how functional nausea in adolescents may be characterized noninvasively by the use of multichannel electrogastrogram (EGG) and magnetogastrogram (MGG) recordings.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Vanderbilt University Medical Center
• Treatments: Cyproheptadine; Ondansetron

Criteria

Inclusion Criteria:

• children ages 8-17 with functional nausea

• normal control participants ages 8-17 who have no known gastrointestinal complications

Exclusion Criteria:

• Those with claustrophobia who cannot lie still under the SQUID for the length of time required.

• Normal participants with known intestinal complications

• Patients with cyclic vomiting syndrome, gastroparesis, malignancy, primary eating disorders, pregnancy, or hyperglycemia

• Morbid obesity (these patients are presumably unable to lie under the current generation of SQUID devices).

• Patients with a history of cardiac arrhythmias or taking anticoagulants will be excluded