Non-operative Management of Pediatric Appendicitis With an Appendicoltih

• Status: Terminated
• Trial end date: 2015-07-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine if non-operative management with antibiotics alone is a feasible treatment alternative for pediatric patients with uncomplicated acute appendicitis with an appendicolith identified on imaging.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Peter Minneci
• Treatments: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antibiotics, Antitubercular; Piperacillin, tazobactam drug combination

Criteria

Inclusion Criteria:

• Age : 7-17 years

• Abdominal pain
• White Blood Cell Count >5 but < 18

• US or CT confirmed early appendicitis plus:

• US:
• CT:

Exclusion Criteria:

• Positive urine pregnancy test

• Pain > 48 hours prior to first antibiotic dose

• Diffuse peritonitis

• History of chronic intermittent abdominal pain

• White Blood Cell count ≤ 5 or ≥ 18

• Absence of appendicolith or any evidence on imaging studies concerning for evolving perforated appendicitis including abscess or phlegmon