Non-invasive Test-guided Tailored Therapy Versus Empiric Treatment for Helicobacter Pylori Infection.
Status:
Recruiting
Trial end date:
2022-04-14
Target enrollment:
Participant gender:
Summary
The aim of our study will be to assess in an open-label, multicenter, randomized controlled
trial whether a tailored therapy guided by a non-invasive antibiotic susceptibility test on
stool samples achieves higher Helicobacter eradication rates than an empiric antibiotic
regimen. For this purpose, consecutive patients with dyspeptic symptoms, diagnosis of
Helicobacter pylori infection and naïve to eradicating treatments will be allocated to either
of the two intervention arms.