Overview Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum Status: Completed Trial end date: 2020-03-29 Target enrollment: Participant gender: Summary The purpose of this research study is to look at how tumors responds to a short course of radiation (5 days) followed by 8 cycles of chemotherapy. Phase: Phase 2 Details Lead Sponsor: Washington University School of MedicineTreatments: FluorouracilFormyltetrahydrofolatesLeucovorinLevoleucovorinOxaliplatinTetrahydrofolates