Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema

• Status: Recruiting
• Trial end date: 2021-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Trial of Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Massachusetts General Hospital
• Collaborator: Himalayan Rescue Association
• Treatments: Nifedipine

Criteria

Inclusion Criteria:

• Healthy adults (age 18-80)

• Travel through Pheriche, Nepal

• Diagnosis of HAPE by symptoms, vital signs, and lung ultrasound

Exclusion Criteria:

• History of chronic respiratory conditions (asthma, COPD, ILD)

• Concomitant pneumonia or aspiration, cardiomyopathy, congestive heart failure

• Kidney disease

• Neurologic disorder

• Cognitive disorder

• Temporary altered mental status

• Use of phosphodiesterase inhibitors or nifedipine prior to diagnosis of HAPE

• Age under 18 or over 80

• Pregnancy