Non Inferiority Trial Investigating Surfactants Administered Via MIST
Status:
Recruiting
Trial end date:
2027-12-01
Target enrollment:
Participant gender:
Summary
RESEARCH DESIGN Multicenter, randomized, controlled trial. RECRUITMENT Entry criteria Preterm
infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical
diagnosis of respiratory distress syndrome. Infants who are on NCPAP and FiO2 ≥0.30 will
randomized to curosurf or infasurf via MIST.
Exclusion criteria Infants will be excluded if there is a congenital anomaly or an
alternative cause for respiratory distress.
Babies who require emergent intubation will not be enrolled in the interventions.
Parental Consent will be obtained prior to randomization.