Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
Osteopenia and osteoporosis cause thinning of bone tissue and loss of bone density over time.
The purpose of this study is to determine the safety and effectiveness of nitroglycerin
ointment for the treatment of osteopenia in postmenopausal women.
Study hypothesis: On average, participants in the base therapy cohort who receive placebo
ointment control and calcium/vitamin D will lose more bone density than participants in the
nitroglycerin cohort over the 36-month period.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Treatments:
Calcium Ergocalciferols Nitric Oxide Nitroglycerin Vitamin D Vitamins