Overview

Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac Surgery

Status:
Completed

Trial end date:
2017-04-14

Target enrollment:
0

Participant gender:
All

Summary

This prospective randomized study evaluates the nephroprotective effects of exogenous nitric oxide delivered to the extracorporeal circulation circuit during cardiac surgery with cardiopulmonary bypass.

Phase:

Phase 1/Phase 2

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Nikolay Kamenshchikov

Treatments:

Nitric Oxide

Criteria

Inclusion Criteria:

Age above 18 years; planned primary cardiac intervention with cardiopulmonary bypass
including coronary artery bypass grafting, valve surgery, and surgical reconstructions of
the left ventricle.

Exclusion Criteria:

Preoperative anemia; the intake of nephrotoxic drugs or the use of X-ray contrast within 72
h before surgery; active phase of endocarditis; emergency surgery; chronic kidney disease;
hematologic diseases accompanied by hemolysis; complications of the surgery and the early
postoperative period.