Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children
Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
Acute chest syndrome is a severe sickle cell disease complication in children requiring blood
transfusion therapy to prevent acute respiratory failure and death. Nitric oxide is a potent
vasodilator that could reverse pulmonary vascular occlusion and restore normal oxygenation.
The randomized trial will test that hypothesis.