Nitrate Patch Use as Treatment of Knee AVN

• Status: Unknown status
• Trial end date: 2019-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The pathogenesis of AVN includes a defective blood supply to the knee joint. Local nitrates induce peripheral vasodilation and may improve blood supply to the affected tissue.

This study aims to test whether the use of a nicotine patch may accelerate the healing process from AVN of the knee.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sheba Medical Center

Criteria

Inclusion Criteria:

• adult patients (18-80 y.o)

• diagnosis of AVN according to MRI

Exclusion Criteria:

• Terminal illness

• Cognitive impairment / any condition disturbing informed concent.

• Nitrate intolerance

• Patients using Cyclic GMP inhibitiors