Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected Children
Status:
Completed
Trial end date:
2006-05-01
Target enrollment:
Participant gender:
Summary
Cryptosporidium parvum (C. parvum) is a parasite that can cause chronic diarrhea and is a
significant problem for HIV infected children in developing countries. C. parvum infection
can be treated with the drug nitazoxanide (NTZ). However, NTZ has not been tested in HIV
infected children. The purpose of this study is to test the safety of NTZ in HIV infected
children who have chronic diarrhea caused by C. parvum.
Study hypothesis: Twice-daily NTZ is safe and well tolerated in HIV infected infants,
children, and adolescents with chronic diarrhea caused by C. parvum infection.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)