Nitazoxanide and Lansoprazole Based Regimens for H. Pylori Management

• Status: Recruiting
• Trial end date: 2022-03-15
• Target enrollment: 0
• Participant gender: All

Summary

The study will evaluate the eradication rate and tolerability of modified LOAD regimens (three antibiotics and a proton pump inhibitor (lansoprazole)) for management of HP infection in treatment-naive patients as well as patients who failed previous therapies.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Liver Institute, Egypt
• Collaborator: Future pharmaceutical industries

Criteria

Inclusion Criteria:

• Patients presented with dyspepsia for more than one month with positive H. pylori antigen test in stool

Exclusion Criteria:

• Treatment with proton pump inhibitors, bismuth, H2 receptor antagonist, or sucralfate within the two weeks before study entry, recent use of antibiotics (within one month), allergy to any of the study drugs, active bleeding, gastric surgery, pregnancy, any current malignancy.