Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality With Mechanical Ventilation
Status:
Not yet recruiting
Trial end date:
2025-07-01
Target enrollment:
Participant gender:
Summary
Dexmedetomidine and ketamine are both suggested for sedation and analgesia in ICU patients
with mechanical ventilation. Recent studies suggest that low-dose dexmedetomidine or
ketamine/esketamine may improve sleep quality of ICU patients. The purpose of this trial is
to observe whether night-time infusion of low-dose dexmedetomidine-esketamine combination can
improve sleep structure of patients with mechanical ventilation in the ICU.