Overview

Nifedipine Versus Magnesium Sulfate for Prevention of Preterm Labor in Symptomatic Placenta Previa

Status:
Completed
Trial end date:
2021-04-30
Target enrollment:
0
Participant gender:
Female
Summary
Antepartum hemorrhage is defined as bleeding from or within the female genital tract, occurring from 28+0 weeks of pregnancy and till delivery of the fetus. it occurs in 3-5% of pregnancies and is an important cause of perinatal and maternal morbidity and mortality worldwide
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Assiut University
Treatments:
Magnesium Sulfate
Nifedipine
Criteria
Inclusion Criteria:

- Estimated gestational age : between 28 weeks and 37 week's gestation

- Confirmed Placenta previa; either major or minor degrees.

- Placenta previa with preterm uterine contractions

Exclusion Criteria:

- Severe attack of bleeding requiring an immediate intervention.

- Fetal heart rates instability or non-reassuring tracing

- Intrauterine fetal death or major fetal anomalies.

- If associated with abruptio placentae

- Patients with known bleeding disorders or on anticoagulant therapy

- Patients with severe medical disorders as myasthenia gravis documented magnesium
toxicity.