Nicotine as an Adjuvant Analgesic for Third Molar Surgery
Status:
Completed
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
Third molar surgery is complicated by pain and swelling for several days after surgery.
Non-steroidal antiinflammatory drugs have been useful in combination with opioids for
treatment. Nicotine has antiinflammatory and pain relieving properties. We will use nicotine
or placebo as a nasal spray before surgery to determine whether nicotine affects pain or
inflammation.