Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia

• Status: Completed
• Trial end date: 2011-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to investigate the relative contributions of nicotine replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on abstinence-induced smoking urges, withdrawal-related negative affect, psychiatric symptoms, cognitive task performance and 90-min ad libitum usual-brand smoking behavior in smokers with schizophrenia and non-psychiatric smokers.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Brown University
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• schizophrenia or no psychiatric illness

• 18 and older

• men and women

• cigarette smokers, 20-50 cigarettes per day

• would like to quit someday

Exclusion Criteria:

• medical conditions excluding transdermal nicotine replacement

• pregnancy or lactation