Nicotine Patch Pretreatment for Smoking Cessation in PTSD

• Status: Completed
• Trial end date: 2013-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study seeks to evaluate the relationship between PTSD, abstinence, and factors associated with relapse in the context of a randomized, clinical smoking cessation trial.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: US Department of Veterans Affairs; VA Office of Research and Development
• Treatments: Bupropion; Nicotine

Criteria

Inclusion Criteria:

• Smokers who smoke 10 or more cigarettes per day in the past year;

• 18-80 years old;

• English speakers;

• medically stable;

• stable on current medication regimen

Exclusion Criteria:

• Pregnant women excluded;

• participants with organic mental disorder, schizophrenia, bipolar disorder, lifetime but not current PTSD, current substance abuse or dependence;

• medical conditions contraindicated with nicotine replacement therapy;

• use other forms of nicotine (cigars, nicotine gum, etc.)