Nicotine Gum Recovery After Colorectal Surgery

• Status: Terminated
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate whether the use of nicotine gum in the postoperative period influences surgical outcome in patients undergoing colorectal surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cleveland Clinic Florida; The Cleveland Clinic
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Able to freely give written informed consent to participate in the study and have signed the Informed Consent Form;

• Due to undergo small and/or large partial bowel resection via laparotomy or laparoscopy;

Exclusion Criteria:

• Prior intestinal surgery

• Mentally incompetent or unable or unwilling to provide informed consent or comply with study procedures

• American Society of Anesthesiologists (ASA) Class IV or V;

• History of abdominal carcinomatosis;

• History of radiation enteritis;

• Children < 18 or adults > 85 years of age

• Pregnant women

• Current cigarette, cigar smokers and chewers of tobacco. ex smokers who quit less than 3 months ago.

• Patients requiring postoperative ventilation, pressor requirement or ICU stay

• Patients with prior cardiovascular disorders