Overview

Niacin/Laropiprant and Endothelial Function

Status:
Completed
Trial end date:
2011-10-01
Target enrollment:
Participant gender:
Summary
Primary objective: To evaluate the impact of 12 weeks' administration of extended release niacin/laropiprant (ERN/LRPT) compared to placebo added to statin therapy on endothelial dependant dilatation of the arterial wall assessed by brachial vasoreactivity in stable coronary heart disease (CHD) patients. Secondary objective: To evaluate the impact of 12 weeks' administration of extended release niacin/laropiprant (ERN/LRPT) compared to placebo added to statin therapy on serum lipids and the parameters of inflammation in stable coronary heart disease (CHD) patients. CHD-coronary heart disease ER-extended release
Phase:
Phase 4
Details
Lead Sponsor:
University Medical Centre Ljubljana
Treatments:
Niacin
Niacinamide
Nicotinic Acids