Nevirapine Study for the Prevention of Maternal-Infant HIV Transmission in Uganda
Status:
Completed
Trial end date:
2007-07-01
Target enrollment:
Participant gender:
Summary
The increase in pediatric HIV infection has a substantial impact on childhood mortality in
the developing world. A number of recent studies suggest that as many as half or more of
mother-to-child HIV transmissions in developing countries occur in late pregnancy or during
labor and delivery. Interventions targeted during the perinatal period have shown to be
effective and to have a significant impact in reducing transmission. The purpose of this
study is to investigate the effectiveness of nevirapine (NVP) plus immunoprophylaxis or
extended NVP dosing regimens in HIV-infected pregnant women and their infants during the
perinatal period.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)