Neuroprotective Effects of Lithium in Patients With Small Cell Lung Cancer Undergoing Radiation Therapy to the Brain
Status:
Completed
Trial end date:
2017-06-05
Target enrollment:
Participant gender:
Summary
This phase I/II trial studies the effects and safety of giving lithium carbonate (lithium) to
patients with small cell lung cancer (SCLC) undergoing radiation therapy to the brain (PCI;
prophylactic cranial irradiation). PCI is used to prevent cancer metastases from returning in
the brain. This treatment can cause short-term memory problems by damaging the hippocampus.
Lithium may help prevent or lessen memory problems caused by PCI by protecting the
hippocampus.