Neuroprotective Effects of ACTH4-10PRO8-GLY9-PRO10
Status:
Completed
Trial end date:
2021-10-30
Target enrollment:
Participant gender:
Summary
The compound ACTH4-10Pro8-Gly9-Pro10 is a synthetic analog molecule of an adrenocorticotropic
hormone (ACTH) short fragment. That is free from hormonal effects and has neuromodulatory
effects. We investigate the neuroprotective effects of ACTH4-10Pro8-Gly9-Pro10 can lessen
neurotoxicity against ketamine in neonatal rats by looking at BDNF expression in the cortex
and hippocampus tissue as well as BDNF blood levels.