The aim of this study is to use magnetic resonance imaging to explore and compare possible de
novo neuroplastic changes induced by the isolated effects of the hypnotic agents sevoflurane
and propofol, respectively. In addition, to explore possible associations between
neuroplastic changes and clinical and/or biochemical outcomes. It is a randomised,
cross-over, single blinded clinical study. N = 30. Female:male ratio 1:1.