Neuropeptides in the Humane Intra- og Extracerebral Circulation.

• Status: Completed
• Trial end date: 2007-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aim at examining whether Sumatriptan changes the plasma values of the neuropeptides vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase activating peptide (PACAP) and the prostanoids 6-keto-PGF1α, and PGE2, PGD2 og PGF2α.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Danish Headache Center
• Collaborators: Bispebjerg Hospital; Glostrup University Hospital, Copenhagen
• Treatments: Sumatriptan

Criteria

Inclusion Criteria:

• healthy volunteers

• 18-50 years,

• 50-100 kg.

• Fertile women must use birth control.

Exclusion Criteria:

• All primary types of headache

• Daily intake of medicine except birth control

• Pregnancy

• Hypertension

• Hypotension

• other chronic disease