Neuromuscular Blockade for Optimising Surgical Conditions During Spinal Surgery
Status:
Unknown status
Trial end date:
2019-05-01
Target enrollment:
Participant gender:
Summary
In the present study, the investigators compare intermediate and deep NMB i.e. the two
extreme regimes of muscle paralysis (neuromuscular block; NMB), (I) patients receiving
intermediate muscle paralysis (''control, conventional NMB'') versus (II) patients with a
deep neuromuscular blockade with rocuronium (''Deep NMB''), will be compared during a
surgical procedure which is considered to be very sensitive for inadequate muscle relaxation,
elective minimally invasive spinal surgery.
The primary objective of this trial is to compare the operation time reduction with the help
of the decreased stiffness of targeted back muscle surrounding the surgical field.
The changed back muscle stiffness also measured as secondary objective goal by a mechanical
tension weighing scale and also taking ultrasonography using shear wave elastography (SWE).
Other observational objectives are divided into the following categories of stakeholders:
patients, surgeons and anesthesiologists', done by collecting the variety of clinical
parameters. The following will be collected and compared.
1. For patients Intraoperative radiation amount, post-anesthetic care unit(PACU) stay,
transfer rate to SICU for post-op. care, post-operative respiratory complication rate,
and total hospital costs.
2. For surgeons Post-operative complications in regard to operation field, and evaluate
surgical conditions using a Visual Analogue Scale(VAS score) in surgeon's side.
3. For anesthesiologists Intraoperative ventilation parameters of patients, and evaluate
surgical conditions using a Visual Analogue Scale(VAS score) in anesthesiologist's side.