Overview

Neuromodulation and Language Acquisition (Project Stage Ia)

Status:
Terminated
Trial end date:
2005-04-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to determine whether levodopa, pergolid, rivastigmine, or modafinil are effective in boosting semantic language acquisition in healthy subjects.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University Hospital Muenster
Treatments:
Levodopa
Modafinil
Rivastigmine
Criteria
Inclusion Criteria:

- Healthy subjects

- 20-35 years old

- Right handedness

- Left language dominance (as assessed by functional transcranial Doppler
ultrasonography [fTCD])

Exclusion Criteria:

- Neurological/psychiatric/metabolic/cardiac disorders

- Asthma

- Known allergic reactions to one of the experimental drugs

- Other drugs affecting the central nervous system

- Leisure drug ingestion during the past 4 weeks (urine test)

- Smoking cessation during the past 2 weeks

- > 6 cups of coffee or energy drinks per day

- > 10 cigarettes per day

- > 50 grams of alcohol per day