Overview

Neurokinin (NK) 1 Antagonist for Pathological Aggression for Harmful, Impulsive, and Self-/Aggressive Behaviour

Status:
Unknown status
Trial end date:
2020-06-01
Target enrollment:
Participant gender:
Summary
Neurokinin (NK) -1 antagonist will be administered to study patients in a double-blind placebo trial. Patients receive assessments including Anger Disorder Scale (ADS) and Modified Overt Aggression Scale (MOAS) and perform computerized study tasks during MRI before the trial begins. Patients receive either one week of the drug or one week of placebo and perform the same tasks and assessments. Then patients receive another week of the alternate pill, followed by another round of tasks during MRI and assessments.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
St. Joseph's Healthcare Hamilton
Collaborator:
University Health Network, Toronto