Overview

Neuroimmune Effects of Opioid Administration

Status:
Completed

Trial end date:
2021-03-10

Target enrollment:

Participant gender:

Summary

Preclinical research indicates acute opioid administration evokes an immune response in the periphery and brain. Here, we will translate those preclinical findings to healthy human volunteers and quantify the neuroimmune response to a morphine challenge using positron emission tomography (PET) imaging with [11C]PBR28.

Phase:

Phase 1

Details

Lead Sponsor:

Yale University

Treatments:

Morphine