Overview

Neuroimaging of Dystonia

Status:
Completed
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to investigate primary cervical dystonia as compared to healthy control subjects and DYT 1 dystonia as compared to healthy control subjects by examining cognitive measures, physical measures, and structural and functional magnetic resonance imaging (MRI). The secondary aim of this study is to investigate a specific drug therapy for primary cervical dystonia to develop a functional MRI (fMRI) research paradigm. The drug, trihexyphenidyl, is FDA approved to treat Parkinson's Disease and is commonly prescribed by physicians as a treatment for symptoms of primary cervical dystonia.
Details
Lead Sponsor:
University of Florida
Collaborator:
Bachmann Strauss Dystonia & Parkinson Foundation, Inc.
Treatments:
Polystyrene sulfonic acid
Trihexyphenidyl