Overview

Neuroblastoma Maintenance Therapy Trial

Status:
Recruiting
Trial end date:
2029-02-01
Target enrollment:
Participant gender:
Summary
Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter, study for patients with neuroblastoma in remission. In this study subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 ± 250 mg/m2 BID (strata 1, 2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study. This study will focus on the use of DFMO in high risk neuroblastoma patients that are in remission as a strategy to prevent recurrence.
Phase:
Phase 2
Details
Lead Sponsor:
Giselle SaulnierSholler
Giselle Sholler
Collaborators:
Beat NB Cancer Foundation
Because of Ezra
KC Pharma
Team Parker for Life
Treatments:
Eflornithine