Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO)
Status:
Recruiting
Trial end date:
2022-07-01
Target enrollment:
Participant gender:
Summary
The Department of Psychiatry at the University of Pittsburgh is conducting a research study
to learn about the changes that occur in the brain when individuals suffer from and then are
treated for depression. The NEMO study has two main purposes. The first is to provide
medication treatment to individuals ages 60 and older who are currently depressed.
The second part of the study involves completing a series of 4 MRIs, which assess changes in
brain function over the course of treatment. This research may help investigators to develop
faster and more effective treatment plans in the future, as brain responses that are detected
early in treatment may predict how well an individual will respond to antidepressant
medication.
Phase:
Phase 4
Details
Lead Sponsor:
Howard Aizenstein University of Pittsburgh
Collaborators:
National Institute of Mental Health (NIMH) Weill Cornell Institute of Geriatric Psychiatry